Cell division and cytokinesis

Cells (Continuity and change) · Cell and nuclear division · note 1 of 4

Cell division and cytokinesisSpec D2.1.1, D2.1.2, D2.1.3

In short

Cytokinesis is the splitting of the cytoplasm of a parent cell between two daughter cells. In animal cells a contractile ring of actin and myosin pinches the membrane inwards; in plant cells vesicles build a new membrane and cell wall across the cell. It is usually equal, but unequal in oogenesis and yeast budding.

All new cells come from existing cells. In cell division a parent cell (often called a mother cell) divides to produce two daughter cells. This is how organisms grow, replace cells and, in unicellular organisms, reproduce.

In eukaryotes, cell division has two parts: the nucleus divides first (mitosis or meiosis), then the cytoplasm divides. Cytokinesis is the splitting of the cytoplasm of the parent cell between the daughter cells.

Cytokinesis in animal and plant cells
FeatureAnimal cellPlant cell
What does the splittingA ring of contractile actin and myosin proteins just inside the cell membrane at the equatorVesicles that gather at the equator
How it happensThe ring contracts and pinches the cell membrane inwards (a cleavage furrow) until the cell is split in twoThe vesicles fuse to form a cell plate, assembling sections of new cell membrane and cell wall that grow out to the existing wall
DirectionFrom the outside inwardsFrom the centre outwards
Two panels: an animal cell pinched in at the equator by a ring of actin and myosin just under the cell membrane, with arrows pointing inwards at the cleavage furrow; and a plant cell with a cell wall where vesicles line up at the equator and fuse into a cell plate (new cell membrane and cell wall) that grows outwards to the existing wall. (opens full size in a new tab)
Cytokinesis: in animal cells a contractile ring of actin and myosin pinches the membrane inwards; in plant cells vesicles fuse to build a cell plate from the centre outwards.

Equal and unequal cytokinesis

Division of the cytoplasm is usually, but not always, equal. Whatever the sizes, both daughter cells must receive at least one mitochondrion, and (in plant cells) plastids such as chloroplasts, plus any other organelle that can only be made by dividing a pre-existing one. A cell cannot build these from scratch.

  • Oogenesis in humans: cytokinesis in both divisions of meiosis is unequal. Almost all the cytoplasm goes to the cell that becomes the ovum, which needs food reserves for the early embryo. The tiny cells produced, called polar bodies, degenerate.
  • Budding in yeast: a small bud grows out of the parent yeast cell, receives a nucleus after mitosis, and then pinches off as a smaller daughter cell.
Common mistake:

Cytokinesis is not part of mitosis. Mitosis is division of the nucleus; cytokinesis is division of the cytoplasm and usually begins in telophase.

Written and checked against the IB Biology SL specification · Updated October 2026

Frequently asked questions

What is the difference between mitosis and meiosis?

Mitosis produces two genetically identical nuclei with the same chromosome number as the parent, for growth and repair. Meiosis has two divisions and produces four haploid nuclei that are genetically different from each other, for sexual reproduction. Meiosis halves the chromosome number and generates diversity through crossing over and random orientation.

What are the phases of mitosis in order?

Prophase, metaphase, anaphase and telophase. Chromosomes condense in prophase, line up on the equator in metaphase, have their sister chromatids pulled to opposite poles in anaphase, and are enclosed in two new nuclear membranes in telophase. Cytokinesis then divides the cytoplasm to give two cells.

How does meiosis cause genetic variation?

Meiosis causes variation in two ways. Crossing over in prophase I swaps sections between non-sister chromatids, making new combinations of alleles. Random orientation of bivalents in metaphase I means each pair lines up independently, giving 2ⁿ possible combinations of chromosomes, about 8.4 million in humans.

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